Structure and Control of a Cell-Cell Adhesion Complex Associated With Spermiation in Rat Seminiferous Epithelium
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چکیده
منابع مشابه
Structure and control of a cell-cell adhesion complex associated with spermiation in rat seminiferous epithelium.
Spermiation, the release of late spermatids from the Sertoli cell, is disrupted by a number of toxicants. Control of the spermiation process, and the proteins that interact to adhere mature spermatids to Sertoli cells, is poorly understood. In these studies we used immunohistochemistry, coimmunoprecipitation/Western blotting, and mass spectrometry to refine an earlier model of sperm adhesion pr...
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Spermiation, the process by which late spermatids separate from the Sertoli cell, is disrupted by a number of toxicants. In this study, we used immunohistochemistry (IHC) to identify some of the proteins associated with the spermatid-Sertoli junction. We confirmed the presence of tubulin, actin, and vinculin at the luminal edge of the seminiferous tubule, and we determined that paxillin is also...
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To assess the regulation of stem factor factor (SCF) gene expression during spermatogenesis, we tested the effects of hormones (FSH, testosterone, and 17beta-estradiol) and some growth factors [transforming growth factor-beta (TGF beta), TGF alpha, tumor necrosis factor-alpha, and activin] on SCF gene expression by using a transillumination-assisted microdisection technique, a seminiferous tubu...
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ژورنال
عنوان ژورنال: Journal of Andrology
سال: 2001
ISSN: 0196-3635
DOI: 10.1002/j.1939-4640.2001.tb03444.x